#ecuimres transcript

Healthcare Social Media Transcript

From: Fri Apr 12 4:00:00 PDT 2013
To: Fri Apr 12 7:15:00 PDT 2013

What is #ecuimres? Who were the influencers during this time period? #ecuimres analytics


Healthcare Conference  - Healthcare Tweet Chats  -  Healthcare Analytics

ecuimchiefs
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Join #ecuimres this morning at 8am in #Vidant Auditorium for #InternalMedicine #Grandrounds on #Hypertension.
nephondemand
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#ecuimres 4/12 #grandrounds: "Getting Ready 4 JNC VIII" by Dr James Powell: profile here ... http://t.co/9aG5WncBlW
ecuimchiefs
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#ecuimres Dr Powell starting off reviewing specific trials that should affect JNC 8. ACCORD, ONTARGET, HYVET, ACCOMPLISH, STITCH, ASCOT
nephondemand
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#ecuimres 4/12 #grandrounds: "Getting Ready 4 JNC VIII": review of antecedent #HYPERTENSION trials of MARPLE, ONTARGET, ACCOMPLISH, HYVET
ecuimchiefs
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#ecuimres Objectives: review data/guidelines for HTN mgmt in pts with CAD, CKD, DM, and elderly
nephondemand
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#ecuimres 4/12 #grandrounds: "Getting Ready 4 JNC VIII": JNC 7 came out in 2003; since then, there r 125,986 different #HYPERTENSION trials
nephondemand
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#ecuimres 4/12 #grandrounds: "Getting Ready 4 JNC VIII": MAPEC study: prospective trial of 448 #hypertensive #diabetes pts 4 CVD M&M
ecuimchiefs
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#ecuimres MAPEC study: pts randomized to take all meds in AM or 1 or more at bedtime. Outcomes measured: CVD mortality and others
nephondemand
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#ecuimres 4/12 #grandrounds: "Getting Ready 4 JNC VIII": MAPEC results: less nighttime dips of BP (abnormal) in those who take meds in AM
ecuimchiefs
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#ecuimres MAPEC study found bedtime dosing group showed significantly lower mean ASLEEP Blood pressures
ecuimchiefs
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#ecuimres MAPEC study lead to demonstration of decreased CVD mortality.
nephondemand
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#ecuimres 4/12 #grandrounds: "Getting Ready 4 JNC VIII": MAPEC results: bedtime dosing of BP meds had lower rates of CVD M&M than AM dosing
nephondemand
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#ecuimres 4/12 #grandrounds: "Getting Ready 4 JNC VIII": KDIGO: Target BP based on albuminuria; if + @ any level, start w/RAS blockade
ecuimchiefs
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#ecuimres #KDIGO BP targets revolve around amount of proteinuria.
ecuimchiefs
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#ecuimres Systematic Review: blood Pressure Target in CKD (Annals) https://t.co/2oAQXREj26
nephondemand
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#ecuimres 4/12 #grandrounds: "Getting Ready 4 JNC VIII": KDIGO used data from 3 trials: MDRD, AASK, REIN-3;
nephondemand
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#ecuimres 4/12 #grandrounds: "Getting Ready 4 JNC VIII": KDIGO suggests but can't confirm that lower BP targets will improve mortality
nephondemand
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#ecuimres 4/12 #grandrounds: "Getting Ready 4 JNC VIII": Mow reviewing INVEST trial. 1st published in 2003 based on JNC 6 criteria but...
nephondemand
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#ecuimres #grandrounds: ...reanalyzed many times since initial publication. Subgroup analyses reveal the "J" curve http://t.co/a3hbgbMglV
ecuimchiefs
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#ecuimres now transitioning to discussion of HCTZ vs Chlorthalidone
nephondemand
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#ecuimres 4/12 #grandrounds: "Getting Ready 4 JNC VIII": now onto HCTZ v chlorthalidone. HCTZ has been defeated by amlodipine, ACE-i
ecuimchiefs
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#ecuimres "Half a Century of Hydrochlorothiazide" http://t.co/J9SrE4gwo9
nephondemand
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#ecuimres 4/12 #grandrounds: "Getting Ready 4 JNC VIII": HTN 2011:57;689-94--HCTZ v chlorthalidone 4 rate of 1st CV event
nephondemand
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#ecuimres 4/12 #grandrounds: "Getting Ready 4 JNC VIII": 4 every 2 mg of HCTZ get same effect as 1 mg of chlorthalidone
ecuimchiefs
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#ecuimres Statement: Chlorthalidone lowers SBP more than HCTZ.
nephondemand
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#ecuimres 4/12 #grandrounds: "Getting Ready 4 JNC VIII": 19% higher risk of CV events in HCTZ arm
ecuimchiefs
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#ecuimres Dr Powell says, "but HCTZ strikes back" http://t.co/YJkE12o9Bt
nephondemand
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#ecuimres 4/12 #grandrounds: "Getting Ready 4 JNC VIII": but HCTZ making a comeback: ANNALS of IM 2013;158(6):447-455.
nephondemand
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#ecuimres 4/12 #grandrounds: "Getting Ready 4 JNC VIII": 1* outcome in this observational cohort same in HCTZ or chlorthalidone;
nephondemand
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#ecuimres #grandrounds: "Getting Ready 4 JNC VIII": chlorthalidone pts 3x more likely 2 b hospitalized 4 hyperkalemia & 1.7x 4 hyponatremia
dilettantemd
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RT @nephondemand: #ecuimres 4/12 #grandrounds: "Getting Ready 4 JNC VIII": JNC 7 came out in 2003; since then, there r 125,986 differen ...
fadelrowaie
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RT @nephondemand: #ecuimres #grandrounds: "Getting Ready 4 JNC VIII": chlorthalidone pts 3x more likely 2 b hospitalized 4 hyperkalemia ...

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