#ecuimres transcript

Healthcare Social Media Transcript

From: Wed Oct 03 0:00:00 PDT 2012
To: Wed Oct 03 13:00:00 PDT 2012

What is #ecuimres? Who were the influencers during this time period? #ecuimres analytics


Healthcare Conference  - Healthcare Tweet Chats  -  Healthcare Analytics

nephondemand
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@RyanMadanickMD @MotherinMed not at ECU. Division Chiefs of Renal & Onc both women; PDs for Renal, #ecuimres & onc women as well.
nephondemand
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#ecuimres #morningreport 10/3: Dr J Brangman will present #polycystic #kidney disease (#ADPKD); profile http://t.co/3hdTJamy #meded
nephondemand
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#ecuimres #morningreport 10/3 #ADPKD: prevalence 1/400-1/1000; most common genetic disorder in the world! #meded http://t.co/Bx1v819U
nephondemand
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#ecuimres #morningreport 10/3: Creatinine is not a good screening marker for #ADPKD #meded
nephondemand
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#ecuimres #morningreport 10/3: 1st mention of #ADPKD by polish King Stefan Bathory in 1586 @ age of 53. It took 347 yrs 2 make the dx #meded
nephondemand
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#ecuimres #morningreport 10/3: 2 known genetic defects can cause #ADPKD; polycystin 1 on chr 16p13.3, polycystin 2 on 4q21 #meded
nephondemand
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#ecuimres #morningreport 10/3 #ADPKD polycystin 1 & 2 r proteins found in tubular kidney cells; inhibit cell prolif by decreasing cAMP#meded
nephondemand
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#ecuimres #morningreport 10/3 #ADPKD #meded pathophysiology shown here http://t.co/bio2i7KK
nephondemand
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#ecuimres #morningreport 10/3: though we r talking a #ADPKD, there r 7 distinct cystic kidney diseases http://t.co/OxTzHMSi #meded
nephondemand
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#ecuimres #morningreport 10/3: best way 2 dx #ADPKD is via ultrasound http://t.co/XI49y2F9 #meded
nephondemand
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#ecuimres #morningreport 10/3: pts w/#ADPKD have a higher risk of cerebral aneurysm ; screening required if family hx is positive #meded
nephondemand
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#ecuimres #morningreport 10/3: pts w/#ADPKD have a 6% prevalence of intracranial aneurysm if family hx -ve; 16% if +ive #meded
nephondemand
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#ecuimres #morningreport 10/3: thankfully cysts of #ADPKD do not have a high risk of malignant transformation #meded
nephondemand
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#ecuimres #morningreport 10/3: bactrim or FQs r lipid soluble & thus gr8 ABX choices for infected cysts #meded
nephondemand
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#ecuimres #morningreport 10/3: pts w/#ADPKD have a higher risk if #nephrolithiasis; rx similar as in the general population #meded
nephondemand
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#ecuimres #morningreport 10/3: pts w/#ADPKD also develop liver cysts (80% prevalence); #meded
nephondemand
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#ecuimres #morningreport 10/3: RAAS system works in overdrive in #ADPKD pts causing #hypertension #meded
nephondemand
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#ecuimres #morningreport 10/3: ACEi use is still not proven 2 retard progression 2 ESRD in #ADPKD pts #meded
nephondemand
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#ecuimres 10/3: HALT Trial is a RCT 2 determine if ACEi + ARB v. ACEi alone can retard cyst growth or progression 2 ESRD in #ADPKD #meded
nephondemand
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#ecuimres #morningreport 10/3: metfformin may decrease cyst growth by activating CFTR and mTOR #meded
nephondemand
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#ecuimres #morningreport 10/3: thus, scientistsvr also looking at TZDs 2 decrease cyst growth in #ADPKD #meded
nephondemand
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#ecuimres 10/3: sandostatin shown 2 decr cyst growth in a placebo double blind trial: JASN 2009 p1052 #meded http://t.co/xJcRLAf5
nephondemand
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#ecuimres #morningreport 10/3: Vaptans r also being investigated: decr renal cAMP levels which would inhibit cyst growth #meded
nephondemand
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#ecuimres #morningreport 10/3: TEMPO Trial investigates the efficacy of tolvaptan; promising results so far http://t.co/JhCs1l5Y #meded
nephondemand
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#ecuimres 10/3: so 4 review: screen w/ultrasound, BP goal <130/80, treat HTN w/ACEi, screen 4 intracranial aneurysm if family hx +ive #meded
nephondemand
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#ecuimres 10/3: @drgregharris asks if polycystin also found in the vasculature 2 account 4 cerebral aneurysm - Dr Bolin states it is unknown
comalliwrites
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RT @nephondemand: #ecuimres #morningreport 10/3: pts w/#ADPKD have a higher risk of cerebral aneurysm ; screening required if family hx ...
nephondemand
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#ecuimres #morningreport 10/3: Dr Leland asks if the cysts r continuous w/nephron lumen. Answer: no. #meded
nephondemand
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#ecuimres #morningreport 10/3: many thanks 2 Drs Leland (GI), Bolin (Chair Medicine), @nephondemand @ecuimchiefs 4 attending today #meded
nephondemand
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RT @comalliwrites: #ecuimres Is it linked with berry aneurysms in particular? -- 6% have aneurysms if no family hx; 16% in +ive family hx
crowdermd
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Enjoyed synopsis of Chairs report by @nephondemand this AM. Poly cystic kidney disease a great #medped topic. #ecuimres
nephondemand
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#ecuimres 10/3: transcript of today's session on #ADPKD is now available http://t.co/NhFLKjdg @ecuimchiefs @SKPDecuim.
comalliwrites
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RT @nephondemand: #ecuimres #morningreport 10/3: pts w/#ADPKD have a higher risk if #nephrolithiasis; rx similar as in the general popu ...
comalliwrites
https://pbs.twimg.com/profile_images/480151409472438272/BtP30-lu_normal.jpeg
RT @nephondemand: #ecuimres #morningreport 10/3: RAAS system works in overdrive in #ADPKD pts causing #hypertension #meded
comalliwrites
https://pbs.twimg.com/profile_images/480151409472438272/BtP30-lu_normal.jpeg
RT @nephondemand: #ecuimres #morningreport 10/3: metfformin may decrease cyst growth by activating CFTR and mTOR #meded
comalliwrites
https://pbs.twimg.com/profile_images/480151409472438272/BtP30-lu_normal.jpeg
RT @nephondemand: #ecuimres #morningreport 10/3: thus, scientistsvr also looking at TZDs 2 decrease cyst growth in #ADPKD #meded
comalliwrites
https://pbs.twimg.com/profile_images/480151409472438272/BtP30-lu_normal.jpeg
RT @nephondemand: #ecuimres #morningreport 10/3: Dr Leland asks if the cysts r continuous w/nephron lumen. Answer: no. #meded

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