#ecuimres transcript

Healthcare Social Media Transcript

From: Fri Oct 12 0:00:00 PDT 2012
To: Fri Oct 12 8:00:00 PDT 2012

What is #ecuimres? Who were the influencers during this time period? #ecuimres analytics


Healthcare Conference  - Healthcare Tweet Chats  -  Healthcare Analytics

ecuimchiefs
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#ecuimres #grandrounds Dr Carter presents, "HIV Prevention: Recent Updates in Pre-Exposure Prophylaxis".
nephondemand
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#ecuimres 10/12 #grandrounds:"#HIV Prevention: Updated in Pre-Exposure #Prophylaxis by http://t.co/7uMTNw0F @ 8 AM EST Today
nephondemand
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#ecuimres 10/12 #grandrounds #HIV #AIDS: Dr Carter's research interests include HIV prevention & prophylaxis since her training days
nephondemand
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#ecuimres 10/12 #grandrounds #HIV #AIDS: objectives= strategies 2 prevent HIV, review the data, & go over CDC recs
ecuimchiefs
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#ecuimres #grandrounds HIV in USA: increased # of ppl living with HIV and steadied trend of new diagnoses.
nephondemand
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#ecuimres 10/12 #grandrounds #HIV #AIDS: from 1996-2007, # of incident HIV pts decreasing, but #of pts dying decreasing only in last 5 yrs
nephondemand
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#ecuimres 10/12 #grandrounds #HIV #AIDS: ~25% of infected pts don't know they have HIV; only 20% of known HIV pts r adherent to ARTs
nephondemand
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#ecuimres 10/12 #AIDS: JAIDS 2010 p271: provides 5 mathematical prediction models 2 estimate prevalence/incidence of #HIV over next 10 yrs
nephondemand
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#ecuimres 10/12: Int'l #AIDS 2012 conference was held in USA 4 1st time in 2/ yrs after a ban 2 prevent #HIV+ pts 2 enter US was lifted
ecuimchiefs
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#ecuimres #grandrounds PEPFAR +ONAP $157 million in new funding for AIDS initiatives globally. Plan to be revealed on World Aids Day 12/1/12
ecuimchiefs
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#ecuimres #grandrounds Today's talk will focus on pre-exposure prophylaxis.
nephondemand
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#ecuimres 10/12 #HIV #AIDS: 4 prevention stages: unexposed, exposed precoital, exposed postcoital, & infected; http://t.co/kfxNgoXN
nephondemand
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#ecuimres 10/12 #grandrounds #HIV #AIDS: NEJM 2011 v365 n6: early ART reduces transmission by 96%
ecuimchiefs
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#ecuimres #grandrounds Prevention of HIV-1 Infection with Early Antiretroviral Therapy: http://t.co/FT6NwWMN
nephondemand
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#ecuimres 10/12 #grandrounds #HIV #AIDS: #FDA has now approved #truvada 4 pre-exposure prophylaxis 4 high risk sexual contact
nephondemand
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#ecuimres 10/12 #grandrounds #HIV #AIDS: #truvada = tenofovir+emtricitabine; mono herapy ONLY 4 preexposure prophylaxis;
ecuimchiefs
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#ecuimres #grandrounds TRUVADA = Tenofovir + Emtricitabine
nephondemand
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#ecuimres 10/12 #grandrounds #HIV #AIDS: CAPRISA 004 trial: tenofovir gel reduced transmission by 39% vs placebo
nephondemand
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#ecuimres 10/12 #grandrounds #HIV #AIDS: iPReX trial: #truvada qd vs placebo in MSM pts: 44% reduction in transmission; conducted in US
ecuimchiefs
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#ecuimres #grandrounds iPrEX study in US, 2500 people, TRUVADA vs placebo. Review key concepts here: http://t.co/UiM1ltlx
nephondemand
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#ecuimres 10/12 #grandrounds #HIV #AIDS: Partners PrEP trial: #tenofovir v #truvada v placebo: 67% reduction in tenofovir, 75% in truvada
nephondemand
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#ecuimres 10/12 #grandrounds #HIV #AIDS: #tenofovir component of #truvada is nephrotoxic and decreases bone density
nephondemand
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#ecuimres 10/12 #grandrounds #HIV #AIDS: add'l trials 2 support preexposure prophylaxis= TDF2, FEM-PrEP, VOICE (still ongoing)
nephondemand
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#ecuimres 10/12 #grandrounds #HIV #AIDS: preexposure prophylaxis can only b given in HIV- pt & must discuss family planning in female pts
ecuimchiefs
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#ecuimres #grandrounds CDC MMWR to release: Interim Guidance for Clinicians Considering Use of Preexposure Prophylaxis http://t.co/4kSeMhPO
nephondemand
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#ecuimres 10/12 #grandrounds #HIV #AIDS: if CrCL <60 of have HBV+, cannot get #truvada b/c can get a fatal flare of hepatitis or #AKI
ecuimchiefs
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#ecuimres #grandrounds Recommendations when beginning PrEP. http://t.co/b5d6TG4U
ecuimchiefs
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#ecuimres #grandrounds Must d/c PrEP if safety concerns, suspicion of HIV
nephondemand
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#ecuimres 10/12 #grandrounds #HIV #AIDS: d/c PrEP once of becomes HIV+, if high risk behavior disappears, by request or poor adherence
ecuimchiefs
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#ecuimres #grandrounds Big challenges are: adherence, acute HIV infection, increase in risky behaviors.
nephondemand
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#ecuimres 10/12 #grandrounds #HIV #AIDS: prevention is a big jigsaw puzzle http://t.co/3DW6EesT
nephondemand
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#ecuimres 10/12 Q: since truvada is a component of HIV treatment, is there concern for developing resistance if used as a prophylactic drug?
nephondemand
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#ecuimres 10/12 #grandrounds #HIV #AIDS: A: data not available but is definitely a concern

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